Publications ROCS

Book chapters

  • Jackowski, O.; Perez-Luna, A. 4.4.38.14 Propargylsilanes (Update 2022). In Science of Synthesis, 2022/3: Knowledge Updates 2022/3; Thieme Verlag, 2022.
  • Roy, M.; Gingras, M. Multihelicenic Platforms from Halogenated Helicenes and Related Precursors. In Helicenes; John Wiley & Sons, Ltd, 2022; pp 263–282.
  • Chemla, F.; Perez-Luna, A. 2.5 Radical–Polar Crossover Reactions. In Free Radicals: Fundamentals and Applications in Organic Synthesis 2; Thieme Verlag, 2021.
  • Piccardi, R.; Micouin, L.; Jackowski, O. The Chemistry of Alkynylaluminum Species. In PATAI’S Chemistry of Functional Groups; Marek, I., Ed.; John Wiley & Sons, Ltd, 2016; pp 1–47.
  • Chemla, F.; Ferreira, F.; Jackowski, O.; Micouin, L.; Perez-Luna, A. Carbon–Carbon Bond Forming Reactions Mediated by Organozinc Reagents. In Metal-Catalyzed Cross-Coupling Reactions and More; Meijere, A. de, Brase, S., Oestreich, M., Eds.; Wiley-VCH Verlag GmbH & Co. KGaA, 2014; pp 279–364.
  • Chemla, F.; Ferreira, F.; Perez-Luna, A.; Micouin, L.; Jackowski, O. Carbon–Carbon Bond-Forming Reactions Mediated by Organomagnesium Reagents. In Metal-Catalyzed Cross-Coupling Reactions and More; Meijere, A. de, Brase, S., Oestreich, M., Eds.; Wiley-VCH Verlag GmbH & Co. KGaA, 2014; pp 365–422.
  • Chemla, F.; Ferreira, F.; Perez-Luna, A. N-Sulfur-Substituted Imines and Their S-Oxidation Products. In Science of Synthesis Knowledge Updates 2012/1; Schaumann E.: Stuttgart, 2012; pp 417–499.
  • C. Botuha, F. Chemla, F. Ferreira, A. Pérez-Luna Aziridines in Natural Product Synthesis. In “Heterocyles in Natural Product Synthesis”, K. C. Majumdar, S. K. Chattopadhyay (Eds.), Wiley-VCH, Weinheim, 2011, pp 3-40.
  • Chemla, F.; Ferreira, F. Carbocupration of Alkynes. in: The Chemistry of Organocopper Reagents, Rappoport, Z.; Marek, I.  eds, Wiley&Sons, 2009, 527-584.
  • Chemla, F.; Ferreira, F.; Roy, B. O,S, Se, Te-acetals ; In: Science Of Synthesis : Acetals: Hal/X and O/O, S, Se, Te, S. V. Ley, S. Warriner Eds; 2007, Vol 29, 801-887.
  • Chemla, F.; Vrancken, E. Reactivity of Oxiranes with Organolithium Reagents. In: The Chemistry of Organolithium Reagents, Rappoport, Z.; Marek, I.  eds, Wiley&Sons, 2004, 1165-1242.

Research Articles

2024

  • Trans-Concerted Addition to Alkynes: the case of Ynamide Silylzincation. Guégan, F.; Chemla, F.; Ferreira. F.; Gérard, H.; Perez-Luna, A.; Halbert, S.;  Chem. Eur. J. 2024, 30, e202401751; https://doi.org/10.1002/chem.202401751
  • Stereoselective Synthesis of 4-Hydroxy-1-Silyl-1-Allenylboranes and Access to 2-Silylethynyl-1,3-Diols. El Haj Brahim, I.; Ishak Dridi, I.; Abderrahim, R.; Fabrice Chemla, F.; Ferreira, F.; Jackowski, O.; Pérez-LunaA.;  Asian J. Org. Chem. 2024, e202400042; https://doi.org/10.1002/ajoc.202400042
  • Stereoselective Double Functionalization of Geminated C(sp3)-Organodimetallic Linchpins. Banchini, F.; Leroux, B.; Le Gall, E.; Presset, M.; Jackowski, O.; Chemla, F. Perez-Luna, A., ChemCatChem, 2024, 16, e202301495; https://doi.org/10.1002/cctc.202301495

2023

  • Ni-catalyzed three-component synthesis of secondary and tertiary C(sp3)-organogermanes, Lorenzini, L. Perez-Luna, A. Chem. Catalysis, 2023, 3, 100860. ; https://doi.org/10.1002/cctc.202301495
  • Transition-Metal-Free Synthesis of Enantioenriched Tertiary and Quaternary α-Chiral Allylsilanes. Pérez Sevillano, R.; Ferreira, F.; Jackowski, O. Chem. Eur. J. 2023, e202302227; http://dx.doi.org/10.1002/chem.202302227
  • ?-(Aminomethyl)-acrylates as acceptors in radical–polar crossover 1,4-additions of dialkylzincs: insights into enolate formation and trapping. Palillero-Cisneros, A.; Gordillo-Guerra, P. G.; Garcia-Alvarez, F. ; Jackowski, O. ; Ferreira, F. ; Chemla, F. ; Teran, J. L. Beilstein J. Org. Chem. 2023, 19, 1443–1451. https://doi.org/10.3762/bjoc.19.103
  • Synthesis of 6-membered germacycles by intramolecular germylzincation of alkynes. Kassamba, S.; Reboli, M.; Perez-Luna, A.; Ferreira, F.; Durandetti, M.Org. Chem. Front. 2023, 10, 3328–3335. https://dx.doi.org/10.1039/D3QO00647F
  • Transition-Metal-Catalyzed Synthesis of α-Chiral Allylsilanes. Sevillano, R. P.; Jackowski, O.; Ferreira, F. Synthesis 2023, 55, 2609–2638. http://dx.doi.org/10.1055/s-0042-1751459
  • Enantioselective Sequential Catalytic Arylation-Fukuyama Cross-coupling of 1,1-Biszincioalkane Linchpins. Banchini, F.; Leroux, B.; Le Gall, E.; Presset, M.; Jackowski, O.; Chemla, F.; Perez-Luna, A. Chem. Eur. J.2023, e202301084 ; http://dx.doi.org/10.1002/chem.202301084.
  • C3-Alkylation of furfural derivatives by continuous flow homogeneous catalysis. Kinkutu, G. K.; Louis, C.; Roy, M.; Blanchard, J.; Oble, J. Beilstein J. Org. Chem.2023,19, 582–592. doi:10.3762/bjoc.19.43

2022

  • Persulfurated Benzene-Cored Asterisks with π-Extended ThioNaphthyl Arms: Synthesis, Structural, Photophysical and Covalent Dynamic Properties. Gahlot, S.; Gradone, A.; Roy, M.; Giorgi, M.; Conti, S.; Ceroni, P.; Villa, M.; Gingras, M. Chemistry – A European Journal2022, 28, e202200797 ; http://dx.doi.org/10.1002/chem.202200797.
  • Modular access to substituted germoles by intramolecular germylzincation. Kassamba, S.; Perez-Luna, A.; Ferreira, F.; Durandetti, M. Chem. Commun.2022, 58, 3901–3904 ; http://dx.doi.org/10.1039/D1CC07163G.
  • Modular synthesis of 2-furyl carbinols from 3-benzyldimethylsilylfurfural platforms relying on oxygen-assisted C–Si bond functionalization. Curpanen, S.; Reichert, P.; Lupidi, G.; Poli, G.; Oble, J.; Perez-Luna, A. Beilstein J. Org. Chem.2022, 18, 1256–1263 ; http://dx.doi.org/10.3762/bjoc.18.131.
  • C3−H Silylation of Furfurylimines: Direct Access to a Novel Biobased Versatile Synthetic Platform Derived from Furfural. Curpanen, S.; Poli, G.; Perez-Luna, A.; Oble, J. Asian J. Org. Chem. 2022, 11, e202200199, http://dx.doi.org/10.1002/ajoc.202200199.
  • C−H Activation Based Functionalization of Furfural Derivatives. Mori, A.; Curpanen, S.; Pezzetta, C.; Perez-Luna, A.; Poli, G.; Oble, J. Eur. J. Org. Chem.2022, n/a, e202200727 ; http://dx.doi.org/10.1002/ejoc.202200727.

2021

  • Radical Germylzincation of Aryl- and Alkyl-Substituted Internal Alkynes. de la Vega-Hernández, K.; Chemla, F.; Ferreira, F.; Jackowski, O.; Perez-Luna, A. Org. Lett.2021, 23, 4426–4430 ; http://dx.doi.org/10.1021/acs.orglett.1c01367.
  • Radical Silyl- and Germylzincation of Propargylic Alcohols. de la Vega-Hernández, K.; Isaac, K.; Chemla, F.; Ferreira, F.; Jackowski, O.; Perez-Luna, A. Helv. Chim. Acta2021, 104, e2100128 ; http://dx.doi.org/10.1002/hlca.202100128.
  • Development of a Radical Silylzincation of (Het)Aryl-Substituted Alkynes and Computational Insights into the Origin of the trans-Stereoselectivity. Romain, E.; Vega-Hernández, K. de la; Guégan, F.; García, J. S.; Fopp, C.; Chemla, F.; Ferreira, F.; Gerard, H.; Jackowski, O.; Halbert, S.; et al. Adv. Synth. Catal.2021, 363, 2634–2647 ; https://doi.org/10.1002/adsc.202001566.
  • C(sp2)−Si Bond Functionalization through Intramolecular Activation by Alkoxides. Curpanen, S.; Poli, G.; Oble, J.; Perez‐Luna, A. Eur. J. Org. Chem.2021, 2021, 1055–1071 ; https://doi.org/10.1002/ejoc.202001458.
  • Radical-Polar Crossover Reactions, Chemla, F.; Perez-Luna, A.; In: Science Of Synthesis : Free Radicals : Fundamentals and Applications in Organic Synthesis, L. Fensterbank, C. Ollivier Eds; 2021, Knowledge Updates 2012/1, 209-337: http://dx.doi.org/10.1055/b000000086.

2020

  • Stereoselective Syntheses, Structures, and Properties of Extremely Distorted Chiral Nanographenes Embedding Hextuple Helicenes. Roy, M.; Berezhnaia, V.; Villa, M.; Vanthuyne, N.; Giorgi, M.; Naubron, J.-V.; Poyer, S.; Monnier, V.; Charles, L.; Carissan, Y.; Hagenbaum-Reignier, D.; Rodriguez, J.; Gingras, M.; Coquerel, Y. Angew. Chem. Int. Ed.2020, 59, 3264–3271 ; http://dx.doi.org/10.1002/anie.201913200.

2018

  • Catalytic Chemoselective and Stereoselective Semihydrogenation of Alkynes to E-Alkenes Using the Combination of Pd Catalyst and ZnI2. Maazaoui, R.; Abderrahim, R.; Chemla, F.; Ferreira, F.; Perez-Luna, A.; Jackowski, O. Org. Lett.2018, 20, 7544–7549 ; http://dx.doi.org/10.1021/acs.orglett.8b03295.
  • Radical Germylzincation of α-Heteroatom-Substituted Alkynes. de la Vega-Hernández, K.; Romain, E.; Coffinet, A.; Bijouard, K.; Gontard, G.; Chemla, F.; Ferreira, F.; Jackowski, O.; Perez-Luna, A. J. Am. Chem. Soc.2018, 140, 17632–17642 ; http://dx.doi.org/10.1021/jacs.8b09851.
  • β‐Amino Propargylic Fluorides through Stereoselective Electrophilic Fluorodesilylation of 4‐Amino‐1‐allenylsilanes. Bochatay, V. N.; Chemla, F.; Ferreira, F.; Jackowski, O.; Pérez-Luna, A. Eur. J. Org. Chem.2018, 3862 ; http://dx.doi.org/10.1002/ejoc.201800862.
  • Triflic Acid as an Efficient Brønsted Acid Promoter for the Umpolung of N‐Ac Indoles in Hydroarylation Reactions. Nandi, R. K.; Perez‐Luna, A.; Gori, D.; Beaud, R.; Guillot, R.; Kouklovsky, C.; Gandon, V.; Vincent, G. Adv. Synth. Catal.2018, 360, 161–172 ; http://dx.doi.org/10.1002/adsc.201701074.
  • Un laboratoire pédagogique à grande échelle: les ateliers bidisciplinaires. F. Chemla, F. Fuster, H. Gérard, A. Markovits, A. Naitabdi, and R. Vuilleumier, L’Actualité Chimique, 2018, no. 433, 41-44.

2017

  • Stereodivergent Synthesis of β-Heteroatom-Substituted Vinylsilanes by Sequential Silylzincation–Copper(I)-Mediated Electrophilic Substitution. Fopp, C.; Isaac, K.; Romain, E.; Chemla, F.; Ferreira, F.; Jackowski, O.; Oestreich, M.; Perez-Luna, A. Synthesis2017, 49, 724–735 ; http://dx.doi.org/10.1055/s-0036-1588106.
  • Synthesis of allenylzinc reagents by 1,2-rearrangement of alkynyl(disilyl)zincates derived from acetylenic epoxides and acetylenic aziridines. Bochatay, V. N.; Debien, L.; Chemla, F.; Ferreira, F.; Jackowski, O.; Perez-Luna, A. C. R. Chim.2017, 20, 609–616 ; http://dx.doi.org/10.1016/j.crci.2017.02.001.
  • Revealing the electrophilicity of N-Ac indoles with FeCl3: a mechanistic study. Beaud, R.; Nandi, R. K.; Perez-Luna, A.; Guillot, R.; Gori, D.; Kouklovsky, C.; Ghermani, N.-E.; Gandon, V.; Vincent, G. Chem. Commun.2017, 53, 5834–5837 ; http://dx.doi.org/10.1039/C7CC02756G.
  • Asymmetric Tandem Conjugate Addition–Aldol Condensation with N-Acryloyloxazolidines Derived from 2-Phenylglycinol. Zelocualtecatl-Montiel, I.; García-Álvarez, F.; Juárez, J. R.; Orea, L.; Gnecco, D.; Mendoza, A.; Chemla, F.; Ferreira, F.; Jackowski, O.; Aparicio, D. M.; et al. Asian J. Org. Chem.2017, 6, 67–70 ; http://dx.doi.org/10.1002/ajoc.201600501.

2016

  • A Well-Defined Low-Valent Cobalt Catalyst Co(PMe3)4 with Dimethylzinc: A Simple Catalytic Approach for the Reductive Dimerization of Benzyl Halides. Fallon, B. J.; Corcé, V.; Amatore, M.; Aubert, C.; Chemla, F.; Ferreira, F.; Perez-Luna, A.; Petit, M. New J. Chem.2016, 40, 9912–9916 ; http://dx.doi.org/10.1039/C6NJ03265F.
  • C2-Alkylation and Alkenylation of Indoles Catalyzed by a Low-Valent Cobalt Complex in the Absence of Reductant. Fallon, B. J.; Derat, E.; Amatore, M.; Aubert, C.; Chemla, F.; Ferreira, F.; Perez-Luna, A.; Petit, M. Org. Lett.2016, 18, 2292–2295 ; http://dx.doi.org/10.1021/acs.orglett.6b00939.
  • 4-Amino-1-Allenylsilanes from 4-Aminopropargylic Acetates through a Silylzincation/Elimination Sequence. Bochatay, V. N.; Neouchy, Z.; Chemla, F.; Ferreira, F.; Jackowski, O.; Pérez-Luna, A. Synthesis2016, 48, 3287–3300 ; http://dx.doi.org/10.1055/s-0035-1562429.
  • Stereodivergent Silylzincation of α-Heteroatom-Substituted Alkynes. Fopp, C.; Romain, E.; Isaac, K.; Chemla, F.; Ferreira, F.; Jackowski, O.; Oestreich, M.; Perez-Luna, A. Org. Lett.2016, 18, 2054–2057 ; http://dx.doi.org/10.1021/acs.orglett.6b00680.
  • Harnessing the Lewis Acidity of HFIP through Its Cooperation with a Calcium(II) Salt: Application to the Aza- Piancatelli Reaction. Leboeuf, D.; Marin, L.; Michelet, B.; Perez-Luna, A.; Guillot, R.; Schulz, E.; Gandon, V. Chem. Eur. J.2016, 22, 16165–16171 ; http://dx.doi.org/10.1002/chem.201603592.
  • Domino Methylenation/Hydrogenation of Aldehydes and Ketones by Combining Matsubara’s Reagent and Wilkinson’s Catalyst. Maazaoui, R.; Pin-Nó, M.; Gervais, K.; Abderrahim, R.; Ferreira, F.; Perez-Luna, A.; Chemla, F.; Jackowski, O. Eur. J. Org. Chem. 2016, 5732–5737 ; http://dx.doi.org/10.1002/ejoc.201601137.
  • Tert-Butanesulfinamides as Nitrogen Nucleophiles in Carbon–Nitrogen Bond Forming Reactions. Ramirez Hernandez, J.; Chemla, F.; Ferreira, F.; Jackowski, O.; Oble, J.; Perez-Luna, A.; Poli, G. Chimia2016, 70, 84–92 ; http://dx.doi.org/10.2533/chimia.2016.84.

2015

  • C–H Activation/Functionalization Catalyzed by Simple, Well-Defined Low-Valent Cobalt Complexes. Fallon, B. J.; Derat, E.; Amatore, M.; Aubert, C.; Chemla, F.; Ferreira, F.; Perez-Luna, A.; Petit, M. J. Am. Chem. Soc.2015, 137, 2448–2451 ; http://dx.doi.org/10.1021/ja512728f.
  • Zinc Radical Transfer Based Modular Approach to Enantiopure Alkylidene-β-Prolines from N-(Tert-Butylsulfinyl)- α-(Aminomethyl)acrylates. Beniazza, R.; Romain, E.; Chemla, F.; Ferreira, F.; Jackowski, O.; Perez-Luna, A. Eur. J. Org. Chem.2015, 7661–7665 ; http://dx.doi.org/10.1002/ejoc.201501173.
  • Ring-Opening of N-Tert-Butanesulfinylethynylaziridines with Lithium Tris(dimethylphenylsilyl)zincate: Stereoselective Access to 4-Amino-1-Allenylsilanes. Bochatay, V. N.; Sanogo, Y.; Chemla, F.; Ferreira, F.; Jackowski, O.; Pérez-Luna, A. Adv. Synth. Catal.2015, 357, 2809–2814 ; http://dx.doi.org/10.1002/adsc.201500347.

2014

  • Reactivity of Tert-Butanesulfinamides in Palladium-Catalyzed Allylic Substitutions. Mistico, L.; Ay, E.; Huynh, V.; Bourderioux, A.; Chemla, F.; Ferreira, F.; Oble, J.; Perez-Luna, A.; Poli, G.; Prestat, G. J. Organomet. Chem. 2014, 760, 124–129 ; http://dx.doi.org/10.1016/j.jorganchem.2013.11.026.
  • Trans-Selective Radical Silylzincation of Ynamides. Romain, E.; Fopp, C.; Chemla, F.; Ferreira, F.; Jackowski, O.; Oestreich, M.; Perez-Luna, A. Angew. Chem. Int. Ed.2014, 53, 11333–11337 ; http://dx.doi.org/10.1002/anie.201407002.
  • Carbon-carbon Forming Reactions Mediated by Organozinc Reagents. Chemla, F.; Ferreira, F.; Jackowski, O.; Micouin, L.; Pérez-Luna, A.; In: Metal-Catalyzed Cross Coupling Reactions, A. de Meijere, S. Bräse, M. Oestreich eds, Wiley-VCH, 2014, 279-364; http://dx.doi.org/10.1002/9783527655588.ch4.
  • Carbon-carbon Forming Reactions Mediated by Organomagnesium Reagents. Chemla, F.; Ferreira, F.; Jackowski, O.; Micouin, L.; Pérez-Luna, A.; In: Metal-Catalyzed Cross Coupling Reactions, A. de Meijere, S. Bräse, M. Oestreich eds, Wiley-VCH, 2014, 365-422; http://dx.doi.org/10.1002/9783527655588.ch5.

2013

  • Homooligomers of Substituted Prolines and β-Prolines: Syntheses and Secondary Structure Investigation. Caumes, C.; Delsuc, N.; Beni Azza, R.; Correia, I.; Chemla, F.; Ferreira, F.; Carlier, L.; Perez Luna, A.; Moumné, R.; Lequin, O.; Karoyan, P. New J. Chem.2013, 37, 1312–1319 ; http://dx.doi.org/10.1039/C3NJ00127J.
  • Radical Zinc-Atom-Transfer-Based Carbozincation of Haloalkynes with Dialkylzincs. Chemla, F.; Dulong, F.; Ferreira, F.; Perez-Luna, A. Beilstein J. Org. Chem.2013, 9, 236–245 ; http://dx.doi.org/10.3762/bjoc.9.28.
  • Conjugated Enyne Synthesis by Rearrangement of Acetylenic Epoxides Mediated by Low-Valence Organotitanium and Organozirconium Reagents. Denichoux, A.; Cyklinsky, M.; Chemla, F.; Ferreira, F.; Pérez-Luna, A. Synlett2013, 24, 1001–1005 ; http://dx.doi.org/10.1055/s-0032-1316894.
  • Three-Carbon Homologation of Diorganozincs with Lithiated Acetylenic Epoxides. Denichoux, A.; Debien, L.; Cyklinsky, M.; Kaci, M.; Chemla, F.; Ferreira, F.; Perez-Luna, A. J. Org. Chem. 2013, 78, 134–145 ; http://dx.doi.org/10.1021/jo302128n.

2012

  • Metallotropic Equilibrium and Configurational Stability of 3-Chloro-1-(Trimethylsilyl)propargyl and -Allenyl Metals: Comparative Study among Lithium, Titanium, and Zinc. Bejjani, J.; Botuha, C.; Chemla, F.; Ferreira, F.; Magnus, S.; Pérez-Luna, A. Organometallics2012, 31, 4876–4885 ; http://dx.doi.org/10.1021/om300420q.
  • Synthesis of Enantiopure 5-Substituted 2,3-Methanopyrrolidines by Cyclization of Enantiopure Alpha-Branched Alpha-N-Homoallylamino Nitriles. Ouizem, S.; Chemla, F.; Ferreira, F.; Perez-Luna, A. Synlett2012, 1374–1378 ; http://dx.doi.org/10.1055/s-0031-1291046.

2011

  • Radical Zinc Atom-Transfer Based Multicomponent Approaches to 3-Alkylidene Tetrahydrofurans. Chemla, F.; Dulong, F.; Ferreira, F.; Nüllen, M. P.; Pérez-Luna, A. Synthesis2011, 1347–1360. http://dx.doi.org/10.1055/s-0030-1259993.
  • Stereoselective Synthesis of syn-β-Amino Propargylic Ethers. Application to the Asymmetric Syntheses of (+)-ß-Conhydrine and (–)-Balanol. Louvel, J.; Chemla, F.; Demont, E.; Ferreira, F.; Pérez-Luna, A.; Voituriez, A. Adv. Synth. Cat.2011, 353, 2137–2151. http://dx.doi.org/10.1002/adsc.201100333.
  • Diastereoselective Synthesis of Homopropargylic N-tert-Butylsulfinylamines. Cyclinsky, M.; Botuha, C.; Chemla, F.; Ferreira, F.; Pérez-Luna, A. Synlett2011, 2681–2684. http://dx.doi.org/10.1021/ol202747p.
  • Synthesis of of (–)-Swainsonine and (–)-8-epi-Swainsonine by the Addition of Allenylmetals to Chiral ?,ß-Alkoxy Sulfinylimines. Louvel, J.; Chemla, F.; Demont, E.; Ferreira, F.; Pérez-Luna, A. Org. Lett.2011, 13, 6452–6455. http://dx.doi.org/10.1021/ol202747p.
  • N-Sulfanyl-, N-Selenanyl-, and N-Tellanylimines and their Oxidation Derivatives. Chemla, F.; Ferreira, F.; Pérez-Luna, A.; In: Science Of Synthesis :Knowledge Updates: Heteroatom analogs of Aldehydes and Ketones, E. Schaumann Ed; 2011, Knowledge Updates 2012/1, 417-499; ISBN : 978-3-13-167181-3.
  • Aziridines in Natural Product Synthesis. Botuha, C.; Chemla, F.; Ferreira, F.; Pérez-Luna, A. inHeterocycles in Natural Product Synthesis, Majumdar K. C., Chattopadhyay, S. K. eds., VCH-Wiley, 2011, pp 3-39; http://dx.doi.org/10.1002/9783527634880.ch1.

2010

  • Asymmetric total synthesis of (+)-6-epi-castanospermine through stereoselective formation of a syn,anti acetylenic 2-amino-1,3-diol stereotriad. Louvel, J.; Botuha, C.; Chemla, F.; Ferreira, F.; Pérez-Luna, A.; Demont, E. Eur. J. Org. Chem.2010, 2921–2926. http://dx.doi.org/10.1002/ejoc.201000202.
  • Cyclization of zincated α-N-homoallylamino nitriles: a new entry to enantiopure 2,3- methanopyrrolidines. Ouizem, S.; Cheramy, S.; Botuha, B.; Chemla, F.; Ferreira, F.; Pérez-Luna, A. Chem. Eur. J., 2010, 16, 12668–12677. http://dx.doi.org/10.1002/chem.201001639.
  • Additions of metal enolates on unactivated carbon-carbon multiple bonds. Denès, F.; Pérez-Luna, A.; Chemla, F. Chem. Rev.2010, 110, 2366–2447. http://dx.doi.org/10.1021/cr800420x.
  • Allenylzincs and tert-butylsulfinimines: a fruitful marriage for synthesis. Botuha, C.; Chemla,  F.; Ferreira, F.; Pérez-Luna, A. Tetrahedon: Asymmetry2010, 21, 1147–1153. http://dx.doi.org/10.1016/j.tetasy.2010.04.044.

2009

  • Stereo- and Enantioselective Synthesis of Acetylenic 2-Amino-1,3-Diol Stereotriads. Voituriez, A.; Pérez-Luna, A.; Ferreira, F.; Botuha C.; Chemla, F. Org. Lett.2009, 11, 931–934. http://dx.doi.org/10.1021/ol802912f.
  • Expeditious Synthesis of a Common Intermediate of L-1-Deoxyallonojirimycin and L-1-Deoxymannojirimycin. Ferreira, F.; Botuha C.; Chemla, F.; Pérez-Luna, A. J. Org. Chem.2009, 74, 2238–2241. http://dx.doi.org/10.1021/jo802757f.
  • Concise Synthesis of (2S,3R)-3-Hydroxy-2-phenylpipezridine: An Advanced Key Intermediate of Human Non-Peptide NK-1 Receptor Antagonists. Hélal, B.; Ferreira, F.; Botuha C.; Chemla, F.; Pérez-Luna, A. Synlett2009, 3115–3118. http://dx.doi.org/10.1055/s-0029-1218308.
  • High-Yielding Synthesis of Sphingoid-Type Bases. Séguin, C.; Ferreira, F.; Botuha C.; Chemla, F.; Pérez-Luna, A. J. Org. Chem.2009, 74, 6986–6992. http://dx.doi.org/10.1021/jo901567q.
  • Tert-Butanesulfinimines: Structure, Synthesis and Synthetic Applications. Botuha, C.; Chemla, F.; Ferreira, F.; Pérez-Luna, A. Chem. Soc. Rev. 2009, 38, 1162–1186. http://dx.doi.org/10.1039/b809772k.
  • Carbocupration of Alkynes. Chemla, F.; Ferreira, F., in: The Chemistry of Organocopper Reagents, Rappoport, Z.; Marek, I.  eds, Wiley&Sons, 2009, 527-584; http://dx.doi.org/10.1002/9780470682531.pat0444.

2008

  • Addition of a 3-alkoxy allenylzinc to N-acyliminium ions: new entry to propargyl syn-1,2-aminoalcohol units. Roy, B; Pérez-Luna, A.; Ferreira, F.; Botuha, C.; Chemla, F. Tetrahedron Lett.2008, 49, 1534–1537. http://dx.doi.org/10.1016/j.tetlet.2007.12.102.
  • Radical-polar crossover domino reactions involving organozinc reagents and β-(allyloxy)-enoates. Giboulot, S.; Pérez-Luna, A.; Botuha, C.; Ferreira, F.; Chemla, F. Tetrahedron Lett. 2008, 49, 3963–3966. http://dx.doi.org/10.1016/j.tetlet.2008.04.108.
  • Zinc(0)/DMF-mediated synthesis of symmetrical carboxylic anhydrides from acyl chlorides. Serieys A.; Botuha, C.; Chemla, F.; Ferreira, F.; Pérez-Luna, A. Tetrahedron Lett.2008, 49, 5322–5323. http://dx.doi.org/10.1016/j.tetlet.2008.06.073.
  • Radical-polar crossover domino reaction involving alkynes: A stereoselective zinc atom radical transfer. Pérez-Luna, A.; Botuha, C.; Ferreira, F.; Chemla, F. Chem ; Eur. J.2008, 14, 8784–8788. http://dx.doi.org/10.1002/chem.200801451.
  • Carbometalation of unactivated Alkenes by Zinc enolate derivatives. Pérez-Luna, A.; Botuha, C.; Ferreira, F.; Chemla, F. New J. Chem.2008, 32, 594–606. http://dx.doi.org/10.1039/b716292h.

2007

  • Diastereocontrolled Synthesis of Enantioenriched 3,4-Disubstituted β-Prolines. Denes, F.; Perez-Luna, A.; Chemla, F. J. Org. Chem.2007, 72, 398–406. http://dx.doi.org/10.1021/jo061603h.
  • Stereoselective Synthesis of Enantioenriched Acetylenic 1,2-Amino Alcohols. Chemla, F.; Ferreira, F.; Gaucher, X.; Palais, L. Synthesis2007, 1235–1241. http://dx.doi.org/10.1055/s-2007-965989.
  • Short and Efficient Asymetric Synthesis of (-)-alpha-Conhydrine. Voituriez, A.; Ferreira, F.; Chemla, F. J. Org. Chem.2007, 72, 5358–5361. https://doi.org/10.1021/jo070760t
  • Asymmetric Synthesis of (–)-1-Hydroxyquinolizidinone, a Common Intermediate for the Syntheses of (–)-Homopumiliotoxin 223G and (–)-Epiquinamide. Voituriez, A.; Ferreira, F.; Perez-Luna, A.; Chemla, F. Org. Lett.2007, 9, 4705–4708. http://dx.doi.org/10.1021/ol701952y.
  • Allenylzinc reagents: new trends and synthetic applications. Botuha, C.; Chemla, F.; Ferreira, F.; Perez-Luna, A.; Roy, B. New J. Chem.2007, 31, 1552–1567. http://dx.doi.org/10.1039/b706541h.
  • O,S, Se, Te-acetals. Chemla, F.; Ferreira, F.; Roy, B.; In: Science Of Synthesis : Acetals: Hal/X and O/O, S, Se, Te, S. V. Ley, S. Warriner Eds; 2007, Vol 29, 801-887; ISBN:978-3-13-118811-3.

2006

  • Synthesis of Diastereoenriched Acetylenic alpha-N-tert-butanesulfinamido(methoxy-methyl)esters. Chemla, F.; Ferreira, F. Synlett2006, 2613-2616; http://dx.doi.org/10.1055/s-2006-951478.
  • Radical-polar Domino Reactions Involving Organozinc and Mixed Organocopper-zinc Reagents. Denes, F.; Perez Luna, A.; Cutri, S.; Chemla, F. Chem: Eur. J.2006, 12, 6506-6513; http://dx.doi.org/10.1002/chem.200600334.
  • Stereoselective Ring-opening of N–tert–butanesulfinylaziridines: Access to Enantiopure Acetylenic alpha-Amino alcohols. Palais, L.; Chemla, F.; Ferreira, F. Synlett2006, 1039-1042; http://dx.doi.org/10.1055/s-2006-939063.

2005

  • Influence of HMPA on the Stereochemical Outcome of the Addition of a Racemic Allenylzinc onto Enantiopure N–tert-Butanesulfinimines: Stereoselective Access to Enantiopure cis Ethynylaziridines. Ferreira, F.; Audouin, M.; Chemla, F. Chem. Eur. J.2005, 11, 5269-5278; http://dx.doi.org/10.1002/chem.200500268.

2004

  • High Kinetic Resolution in the Addition of a Racemic Allenylzinc onto Enantiopure N–tert-Butanesulfinimines: Concise Synthesis of Enantiopure trans 2-Ethynylaziridines. Chemla, F.; Ferreira, F. J. Org. Chem.2004, 69, 8244-8250; http://dx.doi.org/10.1021/jo0490696.
  • Double Deprotonation of Acetylenic Oxiranes: Synthesis of Allenic Ketones through Dilithio Ynenolates. Denichoux, A.; Ferreira, F.; Chemla, F. Org. Lett.2004, 6, 3509-3512; http://dx.doi.org/10.1021/ol048630j.
  • Highly Diastereoselective Syntheses of Propargylic Acid and Homopropargylic Systems. Ferreira, F.; Bejjani, J.; Denichoux, A.; Chemla, F. Synlett, invited paper (account), 2004, 2051-2065; http://dx.doi.org/10.1055/s-2004-832816.

2003

  • N-Trityl Prolinal: An efficient Building Block for the Stereoselective Synthesis of Proline-derived Aminoalcohols. Bejjani, J.; Chemla, F.; Audouin, M. J. Org. Chem.2003, 68, 9747-9752; http://dx.doi.org/10.1021/jo034976g.
  • Domino 1,4-Addition / Carbocyclization Reaction through Radical-polar Crossover Reaction. Denes, F.; Chemla, F.; Normant, J.F. Angew. Chem. Int. Ed.2003, 42, 4043-4046; http://dx.doi.org/10.1002/anie.200250474.
  • Carbocyclization of Zinc Enolates onto Unactivated Double Bonds: A Mechanistic Point of View. Sliwinski, E.; Denes, F.; Chemla, F.; Normant, J.F. C. R.Chimie2003, 67-78; http://dx.doi.org/10.1016/S1631-0748(03)00017-1.

2002

  • Stereoselective Synthesis of Substituted Pyrrolidines by a Domino Michael Addition/Carbocyclization Reaction. Denes, F.; Chemla, F.; Normant, J.F. Eur. J. Org. Chem.2002, 3536-3542; <a href="http://dx.doi.org/10.1002/1099-0690(200211)2002:213.0.CO;2-L”>http://dx.doi.org/10.1002/1099-0690(200211)2002:21<3536::AID-EJOC3536>3.0.CO;2-L.
  • Alkynyl–Oxiranes and Aziridines: Synthesis and Ring Opening Reactions with Carbon Nucleophiles. Chemla, F.; Ferreira, F. Curr. Org. Chem.2002, 6, 539-570; http://dx.doi.org/10.2174/1385272024604916.
  • Diastereoselective Formation of Substituted Pyrrolidine-3-carboxylates. Denes, F.; Chemla, F.; Normant, J.F. Synlett2002, 919-922; http://dx.doi.org/10.1055/s-2002-31898.
  • Diastereoselectivity in the addition of allylzinc reagents to delta-alkoxy-gamma,delta-disubstituted alkenyllithium compounds. Bernard, N.; Chemla, F.; Ferreira, F.; Mostefai, N.; Normant, J.F. Chem. Eur. J. 2002, 8, 3139-3147; <a href="http://dx.doi.org/10.1002/1521-3765(20020715)8:143.0.CO;2-7″>http://dx.doi.org/10.1002/1521-3765(20020715)8:14<3139::AID-CHEM3139>3.0.CO;2-7.
  • A Stereoselective Synthesis of Acetylenic Aziridines. Chemla, F.; Ferreira, F.; Hebbe, V.; Stercklen, E. Eur. J. Org. Chem.2002, 1385-1391; <a href="http://dx.doi.org/10.1002/1099-0690(200204)2002:83.0.CO;2-K”>http://dx.doi.org/10.1002/1099-0690(200204)2002:8<1385::AID-EJOC1385>3.0.CO;2-K.
  • alpha-Oxy Sulfones and sulfoximines : Versatiles Intermediates. Chemla, F. J. Chem. Soc., Perkin Trans. I2002, 275-299; http://dx.doi.org/10.1039/b009523k.
  • Reduction of Sulfonyl Halides: Methyl Methanethiosufonate. Chemla, F.; Karoyan, P. Organic Syntheses2002, 78, 99-103; http://dx.doi.org/10.15227/orgsyn.078.0099.

2001

  • Preparation of Propargylic Carbenoids and Reactions with Carbonyl Compounds – A Stereoselective Synthesis of Propargylic Halohydrins and Oxiranes. Chemla, F.; Bernard, N.; Ferreira, F.; Normant, J. F. Eur. J. Org. Chem.2001, 3295-3300; <a href="http://dx.doi.org/10.1002/1099-0690(200109)2001:173.0.CO;2-T”>http://dx.doi.org/10.1002/1099-0690(200109)2001:17<3295::AID-EJOC3295>3.0.CO;2-T.
  • Configurational Stability of Propargyl Zinc Reagents. Poisson, J.F.; Chemla, F.; Normant, J.F. Synlett2001, 305-307; http://dx.doi.org/10.1055/s-2001-10773.

2000

  • Regioselective SN2 opening of alpha,beta-ethylenic epoxides by RLi-BF3 combination. Alexakis, A.; Vrancken, E.; Mangeney, P.; Chemla, F. J. Chem. Soc., Perkin Trans. I 2000, 3352-3353; http://dx.doi.org/10.1039/b005472k.
  • Fritsch-Buttenberg-Wiechell Rearrangement in the Aliphatic Series. Rezaei, H.; Yamanoi, S.; Chemla, F.; Normant, J. Org. Lett.2000, 2, 419-421; http://dx.doi.org/10.1021/ol991117z.
  • An Easy Synthesis of Aliphatic and Aromatic N-Sulfonyl Aldimines. Chemla, F.; Hebbe, V.; Normant, J. Synthesis2000, 75-77; http://dx.doi.org/10.1055/s-2000-6232.

1999

  • A New Stereoselective Access to N-Benzyl trans Propargylic Aziridines. Chemla, F.; Hebbe, V.; Normant, J. Tetrahedron Letters1999, 40, 8093-8096; http://dx.doi.org/10.1016/S0040-4039(99)01688-3.
  • A New Diastereodivergent Synthesis of 1,2-Disubstituted Homopropargylic Alcohols. Bernard, N.; Chemla, F.; Normant, J. Eur. J. Org. Chem1999, 2067-2078; <a href="http://dx.doi.org/10.1002/(SICI)1099-0690(199909)1999:93.0.CO;2-R”>http://dx.doi.org/10.1002/(SICI)1099-0690(199909)1999:9<2067::AID-EJOC2067>3.0.CO;2-R.
  • A Stereospecific Synthesis of 1,2-Disubstituted Homopropargylic Protected Alcohols from Bromoallenols. Bernard, N.; Chemla, F.; Normant, J. Tetrahedron Letters1999, 40, 1649-1652; http://dx.doi.org/10.1016/S0040-4039(99)00078-7.
  • Metallation of 3-Trimethylsilyl Propargyl Chloride : A Stereoselective Access to trans-Propargylic Oxiranes. Bernard, N.; Chemla, F.; Normant, J. Tetrahedron Letters1999, 40, 75-78; http://dx.doi.org/10.1016/S0040-4039(98)80023-3.

1998

  • An easy and practical Synthesis of Thiosulfonic S-esters. Chemla, F. Synlett1998, 894-896; http://dx.doi.org/10.1055/s-1998-1798.
  • Razionalità dei saperi chimici: schizzo di un progetto di richerche africane. Chemla, F. in: Culture dell’alterità: il territorio africano e le sue rappresentazioni, Casti, E.; Turco, A. eds, Unicopli, , Bergamo, 1998, 519-536 ; ISBN : 978-8-84000-537-9.

1997

1995

1994

  • Configurational stability of chiral organolithium compounds on the time scale of their addition to aldehydes. Hoffmann, R.W.; Julius, M.; Chemla, F.; Ruhland, T.; Frenzen, G. Tetrahedron1994, 50, 6049-6060; http://dx.doi.org/10.1016/S0040-4020(01)90457-0.
  • Oxidation of sulfonylcarbanions with lithium t-butyl peroxide: formation of ß-hydroxysulfones. Chemla, F.; Julia, M.; Uguen, D. Bull. Soc. Chim. Fr.1994, 131, 639-641.

1993

  • Selective monoalkylation of organogembismetallics via an intramolecular nucleophilic substitution. Chemla, F.; Marek, I.; Normant, J.F. Synlett. 1993, 665-666; http://dx.doi.org/10.1055/s-1993-22564.
  • Conversion of primary sulfones into alpha-silyloxysulfones and aldehydes. Chemla, F.; Julia, M.; Uguen, D. Bull. Soc. Chim. Fr.1993, 547-553.
  • A stereoselective C10 + C10 route to retinal. Chemla, F.; Julia, M.; Uguen, D. Bull. Soc. Chim. Fr.1993, 200-205.

1992

1991

  • Preparation of tert-Butoxymethyl Phenyl Sulfone and Its Use in Synthesis as a Formyl Carbanion Equivalent. Chemla, F.; Julia, M.; Uguen, D.; Zhang, D. Synlett,1991, 501-502; http://dx.doi.org/10.1055/s-1991-20777.