Sorbonne University
4 Place Jussieu, 75252 Paris cedex 5
Tower 32-42, 4th floor, office 420
CASCH group

Research interests:

  • Frustrated Lewis pairs for dinitrogen activation
  • Cyanomethylation of ketones by nickel catalysis

Scientific career

  • Since September 2023: Postdoctoral internship at Sorbonne University under the direction of Prof. Jean-Luc Renaud (IPCM, UMR 8232).
  • April 2021-Oct. 2022: Postdoctoral internship at the COBRA laboratory (UMR 6014) at INSA Rouen under the direction of Dr. Jean-François Brière and Dr. Sylvain Oudeyer.
    Topic: Direct cyanomethylation of ketones by nickel catalysis.
  • Oct. 2017- Dec. 2020: Doctoral thesis at the Coordination Chemistry Laboratory (LCC, UPR CNRS 8241) at Paul Sabatier University (Toulouse, France) under the supervision of Prof. Michel Etienne and Dr. Antoine Simonneau.
    Theme: New frustrated Lewis pairs for the activation of dinitrogen and its functionalization.
  • 2014-2017: Master of Chemistry at ENSCM (Mont
    • March 2017-August 2017: Research internship at MANE (Le Bar-sur-Loup, France).
      Theme: Synthesis of organoleptic molecules.
    • June 2016-August 2016: Research internship at the Paris Institute of Molecular Chemistry (IPCM, UMR 8232) of Sorbonne University (Paris, France) under the direction of Dr. Alejandro Perez-Luna.
      Theme: Study of the germylzincation of alkynes and the functionalization of these compounds.
    • 2016: Laboratory project at Cardiff University (Cardiff, Wales) under the direction of Prof. Thomas Wirth.
      Project: Synthesis of carbamates in flow followed by electrochemical cyclization.
    • June 2015-July 2015: Laboratory internship at Paris Cité University (Paris, France) under the direction of Prof. Laurent Micouin.
      Project: Study of the synthesis of aluminum alkylides in continuous flow.

Recent results

  • Cyanomethylation of ketones by nickel catalysis

Selected publications

  1. Assessing Combinations of B(C6F5)3 and N2-Derived Molybdenum Nitrido Complexes For Heterolytic Bond Activation.
    Coffinet, A.; Specklin, D.; Le Dé, Q.; Bennaamane, S.; Muñoz, L.; Vendier, L.; Mézailles, N.; Simonneau, A. Chem. Eur. J. 2023, 29, e202203774.
  2. Nickel-Catalyzed Cyanoalkylation of Ketone Derivatives.
    Coffinet, A.; Levacher, V.; Gillaizeau, I.; Brière, J.-F.; Oudeyer, S. Adv. Synth. Catal. 2023, 365, 156.
  3. Borane-catalysed dinitrogen borylation by 1,3-B–H bond addition.
    Coffinet, A.; Zhang, D.; Vendier, L.; Bontemps, S.; Simonneau, A. Dalton Trans. 2021, 50, 5582.
  4. Push-Pull Activation of N2: Coordination of Lewis Acids to Dinitrogen complexes.
    Coffinet, A.; Specklin, D.; Simonneau, A. Encyl. of Inorg. and Bioinorg. Chem. 2020.
  5. Frustrated Lewis Pair Chemistry Enables N2 Borylation by Formal 1,3-Addition of a B–H Bond in the Coordination Sphere of Tungsten.
    Coffinet, A.; Specklin, D.; Vendier, L.; Simonneau, A.; Etienne, M. Chem. Eur. J. 2019, 25, 14300.